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Inhibition of PKC/MEK pathway suppresses β1-integrin and mitigates breast cancer cells proliferation

Prostaglandin E2 (PGE2) and β1-integrin have been correlated with breast cancer, where both could enhance progression and metastasis. Protein kinase C (PKC) and MEK have played a vital role in breast cancer development. Our study was conducted to elucidate the effect of inhibition of E-prostanoid re...

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Detalles Bibliográficos
Autores principales: EL-Ashmawy, Nahla E., EL-Zamarany, Enas A., Khedr, Naglaa F., Selim, Hend M., Khedr, Eman G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361284/
https://www.ncbi.nlm.nih.gov/pubmed/34408972
http://dx.doi.org/10.1016/j.toxrep.2021.07.012