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Late-in-life neurodegeneration after chronic sleep loss in young adult mice

Chronic short sleep (CSS) is prevalent in modern societies and has been proposed as a risk factor for Alzheimer’s disease (AD). In support, short-term sleep loss acutely increases levels of amyloid β (Aβ) and tau in wild type (WT) mice and humans, and sleep disturbances predict cognitive decline in...

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Detalles Bibliográficos
Autores principales: Owen, Jessica E, Zhu, Yan, Fenik, Polina, Zhan, Guanxia, Bell, Patrick, Liu, Cathy, Veasey, Sigrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361366/
https://www.ncbi.nlm.nih.gov/pubmed/33768250
http://dx.doi.org/10.1093/sleep/zsab057