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Mechanisms and Implications of CDK4/6 Inhibitors for the Treatment of NSCLC
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression in malignant tumor cells and play an important role through complex molecular interactions. Dysregulation of CDK dependent pathways is often found in non-small cell lung cancer, which indicates its vulnerability and can be...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361448/ https://www.ncbi.nlm.nih.gov/pubmed/34395246 http://dx.doi.org/10.3389/fonc.2021.676041 |