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Mechanisms and Implications of CDK4/6 Inhibitors for the Treatment of NSCLC

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression in malignant tumor cells and play an important role through complex molecular interactions. Dysregulation of CDK dependent pathways is often found in non-small cell lung cancer, which indicates its vulnerability and can be...

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Detalles Bibliográficos
Autores principales: Zhang, Jinmeng, Xu, Dayu, Zhou, Yue, Zhu, Zhengfei, Yang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361448/
https://www.ncbi.nlm.nih.gov/pubmed/34395246
http://dx.doi.org/10.3389/fonc.2021.676041