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Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity

Obesity is a metabolic disease characterized by a state of chronic, low-grade inflammation and dominated by pro-inflammatory cytokines such as IL-6. Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme that catalyzes the first step in the kynurenine pathway by transforming l-tryptophan (Trp) into l-kyn...

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Detalles Bibliográficos
Autores principales: Mondanelli, Giada, Albini, Elisa, Orecchini, Elena, Pallotta, Maria Teresa, Belladonna, Maria Laura, Ricci, Giovanni, Grohmann, Ursula, Orabona, Ciriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361489/
https://www.ncbi.nlm.nih.gov/pubmed/34394118
http://dx.doi.org/10.3389/fimmu.2021.713989