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A Shift in Tissue Stiffness During Hippocampal Maturation Correlates to the Pattern of Neurogenesis and Composition of the Extracellular Matrix

Aging changes the mechanical properties of brain tissue, such as stiffness. It has been proposed that the maintenance and differentiation of neural stem cells (NSCs) are regulated in accordance with extracellular stiffness. Neurogenesis is observed in restricted niches, including the dentate gyrus (...

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Detalles Bibliográficos
Autores principales: Ryu, Youngjae, Iwashita, Misato, Lee, Wonyoung, Uchimura, Kenji, Kosodo, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361493/
https://www.ncbi.nlm.nih.gov/pubmed/34393762
http://dx.doi.org/10.3389/fnagi.2021.709620