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Prophylactic effects or withdrawal reactions? An analysis of time-to-event data from antidepressant relapse prevention trials submitted to the FDA

BACKGROUND: Relapse prevention trials build the scientific foundation for recommendation of antidepressant continuation and maintenance therapy. However, the validity of the evidence is disputed and may be biased due to withdrawal confounding. METHODS: We analysed survival curves from all antidepres...

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Detalles Bibliográficos
Autores principales: Hengartner, Michael P., Plöderl, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361519/
https://www.ncbi.nlm.nih.gov/pubmed/34394912
http://dx.doi.org/10.1177/20451253211032051