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Glutaminolysis is involved in the activation of mTORC1 in in vitro‐produced porcine embryos

Glutamine supplementation to porcine embryo culture medium improves development, increases leucine consumption, and enhances mitochondrial activity. In cancer cells, glutamine has been implicated in the activation of mechanistic target of rapamycin complex 1 (mTORC1) to support rapid proliferation....

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Detalles Bibliográficos
Autores principales: Chen, Paula R., Lucas, Caroline G., Spate, Lee D., Prather, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361685/
https://www.ncbi.nlm.nih.gov/pubmed/34075648
http://dx.doi.org/10.1002/mrd.23516