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Balancing DNA repair to prevent ageing and cancer
DNA damage is a constant stressor to the cell. Persistent damage to the DNA over time results in an increased risk of mutation and an accumulation of mutations with age. Loss of efficient DNA damage repair can lead to accelerated ageing phenotypes or an increased cancer risk, and the trade-off betwe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Academic Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361780/ https://www.ncbi.nlm.nih.gov/pubmed/34102225 http://dx.doi.org/10.1016/j.yexcr.2021.112679 |