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The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS
Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral sclerosis (ALS). Immune cells trafficking from the blood also infiltrate the affected CNS parenchyma and contribute to neuroinflammation. Mast cel...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361844/ https://www.ncbi.nlm.nih.gov/pubmed/34389060 http://dx.doi.org/10.1186/s40478-021-01241-3 |