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The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS

Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral sclerosis (ALS). Immune cells trafficking from the blood also infiltrate the affected CNS parenchyma and contribute to neuroinflammation. Mast cel...

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Detalles Bibliográficos
Autores principales: Kovacs, Mariángeles, Alamón, Catalina, Maciel, Cecilia, Varela, Valentina, Ibarburu, Sofía, Tarragó, Lucas, King, Peter H., Si, Ying, Kwon, Yuri, Hermine, Olivier, Barbeito, Luis, Trias, Emiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361844/
https://www.ncbi.nlm.nih.gov/pubmed/34389060
http://dx.doi.org/10.1186/s40478-021-01241-3