Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a eukaryotic, translation-dependent degradation pathway that targets mRNAs with premature termination codons and also regulates the expression of some mRNAs that encode full-length proteins. Although many genes express NMD-sensitive transcripts, iden...

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Detalles Bibliográficos
Autores principales: Karousis, Evangelos D., Gypas, Foivos, Zavolan, Mihaela, Mühlemann, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361881/
https://www.ncbi.nlm.nih.gov/pubmed/34389041
http://dx.doi.org/10.1186/s13059-021-02439-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361881/
https://www.ncbi.nlm.nih.gov/pubmed/34389041
http://dx.doi.org/10.1186/s13059-021-02439-3

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