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Quantifying the natural variation in lesion counts over time in untreated hidradenitis suppurativa: Implications for outcome measures and trial design

BACKGROUND: Hidradenitis suppurativa (HS) demonstrates high placebo response rates in clinical trials, possibly due to the natural variability of the disease. No quantification of variability in lesion counts of untreated disease has been undertaken. OBJECTIVE: To quantify the variability of untreat...

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Detalles Bibliográficos
Autores principales: Frew, John W., Jiang, Caroline S., Singh, Neha, Navrazhina, Kristina, Vaughan, Roger, Krueger, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361889/
https://www.ncbi.nlm.nih.gov/pubmed/34409342
http://dx.doi.org/10.1016/j.jdin.2020.09.005