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Quantifying the natural variation in lesion counts over time in untreated hidradenitis suppurativa: Implications for outcome measures and trial design
BACKGROUND: Hidradenitis suppurativa (HS) demonstrates high placebo response rates in clinical trials, possibly due to the natural variability of the disease. No quantification of variability in lesion counts of untreated disease has been undertaken. OBJECTIVE: To quantify the variability of untreat...
Autores principales: | Frew, John W., Jiang, Caroline S., Singh, Neha, Navrazhina, Kristina, Vaughan, Roger, Krueger, James G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361889/ https://www.ncbi.nlm.nih.gov/pubmed/34409342 http://dx.doi.org/10.1016/j.jdin.2020.09.005 |
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