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Low‐affinity but high‐avidity interactions may offer an explanation for IgE‐mediated allergen cross‐reactivity

BACKGROUND: Allergy is a global disease with overall frequencies of >20%. Symptoms vary from irritating local itching to life‐threatening systemic anaphylaxis. Even though allergies are allergen‐specific, there is a wide range of cross‐reactivities (eg apple and latex) that remain largely unexpla...

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Detalles Bibliográficos
Autores principales: Chang, Xinyue, Zha, Lisha, Wallimann, Alexandra, Mohsen, Mona O., Krenger, Pascal, Liu, Xuelan, Vogel, Monique, Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361967/
https://www.ncbi.nlm.nih.gov/pubmed/33866583
http://dx.doi.org/10.1111/all.14864