Cargando…
On‐demand treatment with the iron chelator deferasirox is ineffective in preventing blood‐induced joint damage in haemophilic mice
INTRODUCTION: Early intervention in the devastating process of haemophilic arthropathy (HA) is highly desirable, but no disease‐modifying therapy is currently available. Considering the pivotal role of iron in the development of HA, iron chelation is considered a promising therapeutic approach. A pr...
Autores principales: | Pulles, Astrid E., van Vulpen, Lize F. D., Coeleveld, Katja, Mastbergen, Simon C., Schutgens, Roger E. G., Lafeber, Floris P. J. G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361985/ https://www.ncbi.nlm.nih.gov/pubmed/34043875 http://dx.doi.org/10.1111/hae.14328 |
Ejemplares similares
-
Proteoglycan synthesis rate as a novel method to measure blood‐induced cartilage degeneration in non‐haemophilic and haemophilic rats
por: Pulles, Astrid E., et al.
Publicado: (2020) -
Ankle joint distraction is a promising alternative treatment for patients with severe haemophilic ankle arthropathy
por: van Bergen, Eline D. P., et al.
Publicado: (2022) -
Pharmacogenetic Study of Deferasirox, an Iron Chelating Agent
por: Lee, Ji Won, et al.
Publicado: (2013) -
Iron Chelation Therapy with Deferasirox in the Management of Iron Overload in Primary Myelofibrosis
por: Elli, Elena Maria, et al.
Publicado: (2014) -
Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma
por: Saeki, Issei, et al.
Publicado: (2016)