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Hi‐C 3.0: Improved Protocol for Genome‐Wide Chromosome Conformation Capture

The intricate folding of chromatin enables living organisms to store genomic material in an extremely small volume while facilitating proper cell function. Hi‐C is a chromosome conformation capture (3C)‐based technology to detect pair‐wise chromatin interactions genome‐wide, and has become a benchma...

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Detalles Bibliográficos
Autores principales: Lafontaine, Denis L., Yang, Liyan, Dekker, Job, Gibcus, Johan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362010/
https://www.ncbi.nlm.nih.gov/pubmed/34286910
http://dx.doi.org/10.1002/cpz1.198