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LEAP‐2/ghrelin interplay in adult growth hormone deficiency: Cause or consequence? A pilot study

Ghrelin and its endogenous antagonist liver‐expressed antimicrobial peptide‐2 (LEAP‐2) are involved in GH secretion and glucose/lipids metabolism. LEAP‐2 expression in conditions of metabolic impairment may be upregulated, usually pairing with a concomitant reduction in ghrelin secretion. Adult grow...

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Detalles Bibliográficos
Autores principales: Vergani, Edoardo, Bruno, Carmine, Gavotti, Cesare, Aversa, Luigi Simone, Martire, Maria, Mancini, Antonio, Currò, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362053/
https://www.ncbi.nlm.nih.gov/pubmed/33991145
http://dx.doi.org/10.1002/iub.2504