Modulation of Src Kinase Activity by Selective Substrate Recognition with Pseudopeptidic Cages

The selective recognition of tyrosine residues in peptides is an appealing approach to inhibiting their tyrosine kinase (TK)‐mediated phosphorylation. Herein, we describe pseudopeptidic cages that efficiently protect substrates from the action of the Src TK enzyme, precluding the corresponding Tyr p...

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Detalles Bibliográficos
Autores principales: Tapia, Lucía, Solozabal, Naiara, Solà, Jordi, Pérez, Yolanda, Miller, W. Todd, Alfonso, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362067/
https://www.ncbi.nlm.nih.gov/pubmed/33904620
http://dx.doi.org/10.1002/chem.202100990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362067/
https://www.ncbi.nlm.nih.gov/pubmed/33904620
http://dx.doi.org/10.1002/chem.202100990

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