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One‐Step Chemo‐, Regio‐ and Stereoselective Reduction of Ketosteroids to Hydroxysteroids over Zr‐Containing MOF‐808 Metal‐Organic Frameworks

Zr‐containing MOF‐808 is a very promising heterogeneous catalyst for the selective reduction of ketosteroids to the corresponding hydroxysteroids through a Meerwein‐Ponndorf‐Verley (MPV) reaction. Interestingly, the process leads to the diastereoselective synthesis of elusive 17α‐hydroxy derivatives...

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Detalles Bibliográficos
Autores principales: Mautschke, H.‐H., Llabrés i Xamena, F. X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362071/
https://www.ncbi.nlm.nih.gov/pubmed/33998732
http://dx.doi.org/10.1002/chem.202100967