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Liposomes with Water as a pH‐Responsive Functionality for Targeting of Acidic Tumor and Infection Sites

A lipid named DCPA was synthesized under microwave‐assisted heating. DCPA possesses a pyridine betaine, hydrophilic group that can be complexed with water through hydrogen bonding (DCPA‐H(2)O). DCPA‐H(2)O liposomes became protonated relatively fast already at pH<6.8, due to the high HOMO binding...

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Detalles Bibliográficos
Autores principales: Wang, Da‐Yuan, Yang, Guang, van der Mei, Henny C., Ren, Yijin, Busscher, Henk J., Shi, Linqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362074/
https://www.ncbi.nlm.nih.gov/pubmed/34028150
http://dx.doi.org/10.1002/anie.202106329