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Liposomes with Water as a pH‐Responsive Functionality for Targeting of Acidic Tumor and Infection Sites
A lipid named DCPA was synthesized under microwave‐assisted heating. DCPA possesses a pyridine betaine, hydrophilic group that can be complexed with water through hydrogen bonding (DCPA‐H(2)O). DCPA‐H(2)O liposomes became protonated relatively fast already at pH<6.8, due to the high HOMO binding...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362074/ https://www.ncbi.nlm.nih.gov/pubmed/34028150 http://dx.doi.org/10.1002/anie.202106329 |