Fluorescent Indolo[3,2‐a]phenazines against Toxoplasma gondii: Concise Synthesis by Gold‐Catalyzed Cycloisomerization with 1,2‐Silyl Migration and ipso‐Iodination Suzuki Sequence

A gold‐catalyzed cycloisomerization of 2‐indolyl‐3‐[(trimethylsilyl)ethynyl)]quinoxalines with concomitant 1,2‐silyl shift forms 6‐(trimethylsilyl)indolo[3,2‐a]phenazines in moderate to excellent yield. These silylated heterocycles are readily transformed into 6‐aryl‐indolo[3,2‐a]phenazines in moder...

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Detalles Bibliográficos
Autores principales: Merkt, Franziska K., Mazzone, Flaminia, Sazzadeh, Shabnam Shaneh, Bonda, Lorand, Hinz, Larissa K. E., Gruber, Irina, Buchholz, Karin, Janiak, Christoph, Pfeffer, Klaus, Müller, Thomas J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362127/
https://www.ncbi.nlm.nih.gov/pubmed/33881786
http://dx.doi.org/10.1002/chem.202101391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362127/
https://www.ncbi.nlm.nih.gov/pubmed/33881786
http://dx.doi.org/10.1002/chem.202101391

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