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Fluorescent Indolo[3,2‐a]phenazines against Toxoplasma gondii: Concise Synthesis by Gold‐Catalyzed Cycloisomerization with 1,2‐Silyl Migration and ipso‐Iodination Suzuki Sequence
A gold‐catalyzed cycloisomerization of 2‐indolyl‐3‐[(trimethylsilyl)ethynyl)]quinoxalines with concomitant 1,2‐silyl shift forms 6‐(trimethylsilyl)indolo[3,2‐a]phenazines in moderate to excellent yield. These silylated heterocycles are readily transformed into 6‐aryl‐indolo[3,2‐a]phenazines in moder...
Autores principales: | Merkt, Franziska K., Mazzone, Flaminia, Sazzadeh, Shabnam Shaneh, Bonda, Lorand, Hinz, Larissa K. E., Gruber, Irina, Buchholz, Karin, Janiak, Christoph, Pfeffer, Klaus, Müller, Thomas J. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362127/ https://www.ncbi.nlm.nih.gov/pubmed/33881786 http://dx.doi.org/10.1002/chem.202101391 |
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