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Programmed Death Ligand 1 Is Overexpressed in Liver Macrophages in Chronic Liver Diseases, and Its Blockade Improves the Antibacterial Activity Against Infections

BACKGROUND AND AIMS: Bacterial infections are common and severe in cirrhosis, but their pathogenesis is poorly understood. Dysfunction of liver macrophages may play a role, but information about their function in cirrhosis is limited. Our aims were to investigate the specific profile and function of...

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Detalles Bibliográficos
Autores principales: Pose, Elisa, Coll, Mar, Martínez‐Sánchez, Celia, Zeng, Zhutian, Surewaard, Bas G. J., Català, Cristina, Velasco‐de Andrés, María, Lozano, Juan José, Ariño, Sílvia, Fuster, David, Niñerola‐Bazán, Aida, Graupera, Isabel, Muñoz, Érica, Lozano, Francisco, Sancho‐Bru, Pau, Kubes, Paul, Ginès, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362175/
https://www.ncbi.nlm.nih.gov/pubmed/33219516
http://dx.doi.org/10.1002/hep.31644