The Desensitized Channelrhodopsin‐2 Photointermediate Contains 13 ‐cis, 15 ‐syn Retinal Schiff Base

Channelrhodopsin‐2 (ChR2) is a light‐gated cation channel and was used to lay the foundations of optogenetics. Its dark state X‐ray structure has been determined in 2017 for the wild‐type, which is the prototype for all other ChR variants. However, the mechanistic understanding of the channel functi...

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Detalles Bibliográficos
Autores principales: Becker‐Baldus, Johanna, Leeder, Alexander, Brown, Lynda J., Brown, Richard C. D., Bamann, Christian, Glaubitz, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362212/
https://www.ncbi.nlm.nih.gov/pubmed/33973334
http://dx.doi.org/10.1002/anie.202015797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362212/
https://www.ncbi.nlm.nih.gov/pubmed/33973334
http://dx.doi.org/10.1002/anie.202015797

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