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The Desensitized Channelrhodopsin‐2 Photointermediate Contains 13 ‐cis, 15 ‐syn Retinal Schiff Base
Channelrhodopsin‐2 (ChR2) is a light‐gated cation channel and was used to lay the foundations of optogenetics. Its dark state X‐ray structure has been determined in 2017 for the wild‐type, which is the prototype for all other ChR variants. However, the mechanistic understanding of the channel functi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362212/ https://www.ncbi.nlm.nih.gov/pubmed/33973334 http://dx.doi.org/10.1002/anie.202015797 |