Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes

A direct and asymmetric aldol reaction of N‐acyl thiazinanethiones with aromatic aldehydes catalyzed by chiral nickel(II) complexes is reported. The reaction gives the corresponding O‐TIPS‐protected anti‐aldol adducts in high yields and with remarkable stereocontrol and atom economy. Furthermore, th...

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Detalles Bibliográficos
Autores principales: Kennington, Stuart C. D., Teloxa, Saul F., Mellado‐Hidalgo, Miguel, Galeote, Oriol, Puddu, Sabrina, Bellido, Marina, Romea, Pedro, Urpí, Fèlix, Aullón, Gabriel, Font‐Bardia, Mercè
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362213/
https://www.ncbi.nlm.nih.gov/pubmed/33872449
http://dx.doi.org/10.1002/anie.202104352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362213/
https://www.ncbi.nlm.nih.gov/pubmed/33872449
http://dx.doi.org/10.1002/anie.202104352

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