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Evaluation of the pharmacokinetics of prednisolone in paediatric patients with acute lymphoblastic leukaemia treated according to Dutch Childhood Oncology Group protocols and its relation to treatment response

Glucocorticoids form the backbone of paediatric acute lymphoblastic leukaemia (ALL) treatment. Many studies have been performed on steroid resistance; however, few studies have addressed the relationship between dose, concentration and clinical response. The aim of the present study was to evaluate...

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Detalles Bibliográficos
Autores principales: Sassen, Sebastiaan D. T., Mathôt, Ron A. A., Pieters, Rob, de Haas, Valérie, Kaspers, Gertjan J. L., van den Bos, Cor, Tissing, Wim J. E., te Loo, D. Maroeska W. W., Bierings, Marc B., van der Sluis, Inge M., Zwaan, C. Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362215/
https://www.ncbi.nlm.nih.gov/pubmed/34060065
http://dx.doi.org/10.1111/bjh.17572