The transmembrane domain and luminal C-terminal region independently support invariant chain trimerization and assembly with MHCII into nonamers

BACKGROUND: Invariant chain (CD74, Ii) is a multifunctional protein expressed in antigen presenting cells. It assists the ER exit of various cargos and serves as a receptor for the macrophage migration inhibitory factor. The newly translated Ii chains trimerize, a structural feature that is not read...

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Detalles Bibliográficos
Autores principales: Cloutier, Maryse, Fortin, Jean-Simon, Thibodeau, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362237/
https://www.ncbi.nlm.nih.gov/pubmed/34384367
http://dx.doi.org/10.1186/s12865-021-00444-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362237/
https://www.ncbi.nlm.nih.gov/pubmed/34384367
http://dx.doi.org/10.1186/s12865-021-00444-6

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