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Peptide vaccine-conjugated mesoporous carriers synergize with immunogenic cell death and PD-L1 blockade for amplified immunotherapy of metastatic spinal

The clinical treatment of metastatic spinal tumor remains a huge challenge owing to the intrinsic limitations of the existing methods. Programmed cell death protein 1 (PD1)/programmed cell death ligand 1 (PD-L1) pathway blockade has been explored as a promising immunotherapeutic strategy; however, t...

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Detalles Bibliográficos
Autores principales: Wang, Zhenqing, Chen, Liang, Ma, Yiqun, Li, Xilei, Hu, Annan, Wang, Huiren, Wang, Wenxing, Li, Xiaomin, Tian, Bo, Dong, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362242/
https://www.ncbi.nlm.nih.gov/pubmed/34384429
http://dx.doi.org/10.1186/s12951-021-00975-5