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Transcriptome and Function of Novel Immunosuppressive Autoreactive Invariant Natural Killer T Cells That Are Absent in Progressive Multiple Sclerosis

BACKGROUND AND OBJECTIVE: The aim of this study was to determine whether natural killer T (NKT) cells, including invariant (i) NKT cells, have clinical value in preventing the progression of multiple sclerosis (MS) by examining the mechanisms by which a distinct self-peptide induces a novel, protect...

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Detalles Bibliográficos
Autores principales: Carrión, Belinda, Liu, Yawei, Hadi, Mahdieh, Lundstrom, Jon, Christensen, Jeppe Romme, Ammitzbøll, Cecilie, Dziegiel, Morten Hanefeld, Sørensen, Per Soelberg, Comabella, Manuel, Montalban, Xavier, Sellebjerg, Finn, Issazadeh-Navikas, Shohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362604/
https://www.ncbi.nlm.nih.gov/pubmed/34385365
http://dx.doi.org/10.1212/NXI.0000000000001065