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Intrinsic Morphologic and Physiologic Development of Human Derived Retinal Ganglion Cells In Vitro

PURPOSE: Human retinal ganglion cells (hRGC) derived from human pluripotent stem cells are promising candidates to model, protect, and replace degenerating RGCs. Here, we examined intrinsic morphologic and physiologic development of hRGCs. METHODS: We used CRISPR-Cas9 to selectively express tdTomato...

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Detalles Bibliográficos
Autores principales: Risner, Michael L., Pasini, Silvia, Chamling, Xitiz, McGrady, Nolan R., Goldberg, Jeffrey L., Zack, Donald J., Calkins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362626/
https://www.ncbi.nlm.nih.gov/pubmed/34383881
http://dx.doi.org/10.1167/tvst.10.10.1