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Preclinical Evaluation of the Safety and Efficacy of Cryopreserved Bone Marrow Mesenchymal Stromal Cells for Corneal Repair
PURPOSE: Mesenchymal stromal cells (MSCs) have been shown to enhance tissue repair as a cell-based therapy. In preparation for a phase I clinical study, we evaluated the safety, dosing, and efficacy of bone marrow–derived MSCs after subconjunctival injection in preclinical animal models of mice, rat...
Autores principales: | Putra, Ilham, Shen, Xiang, Anwar, Khandaker N., Rabiee, Behnam, Samaeekia, Ravand, Almazyad, Enmar, Giri, Pushpanjali, Jabbehdari, Sayena, Hayat, Mohammed R., Elhusseiny, Abdelrahman M., Ghassemi, Mahmood, Mahmud, Nadim, Edward, Deepak P., Joslin, Charlotte E., Rosenblatt, Mark I., Dana, Reza, Eslani, Medi, Hematti, Peiman, Djalilian, Ali R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362636/ https://www.ncbi.nlm.nih.gov/pubmed/34383879 http://dx.doi.org/10.1167/tvst.10.10.3 |
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