N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats

The aim of this study was to investigate the changes of TLR4/NLRP3 signal during hepatic ischemia-reperfusion injury (HIRI) and to verify whether N-acetyl-L-tryptophan (L-NAT) protected hepatocytes by regulating the activation of TLR4/NLRP3 signal. We have established the rat HIRI model and H(2)O(2)...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Yitong, Yu, Shuna, Wang, Jianxin, Li, Wanzhen, Li, Huiting, Bai, Chen, Sheng, Yaxin, Li, Ming, Wang, Chenchen, Liu, Jiao, Xie, Peitong, Wang, Can, Jiang, Jiying, Li, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362669/
https://www.ncbi.nlm.nih.gov/pubmed/34434653
http://dx.doi.org/10.7717/peerj.11909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362669/
https://www.ncbi.nlm.nih.gov/pubmed/34434653
http://dx.doi.org/10.7717/peerj.11909

Ejemplares similares