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N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats

The aim of this study was to investigate the changes of TLR4/NLRP3 signal during hepatic ischemia-reperfusion injury (HIRI) and to verify whether N-acetyl-L-tryptophan (L-NAT) protected hepatocytes by regulating the activation of TLR4/NLRP3 signal. We have established the rat HIRI model and H(2)O(2)...

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Detalles Bibliográficos
Autores principales:	Pan, Yitong, Yu, Shuna, Wang, Jianxin, Li, Wanzhen, Li, Huiting, Bai, Chen, Sheng, Yaxin, Li, Ming, Wang, Chenchen, Liu, Jiao, Xie, Peitong, Wang, Can, Jiang, Jiying, Li, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2021
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362669/ https://www.ncbi.nlm.nih.gov/pubmed/34434653 http://dx.doi.org/10.7717/peerj.11909

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