Icaritin protects SH-SY5Y cells transfected with TDP-43 by alleviating mitochondrial damage and oxidative stress

BACKGROUND: The aim of this study was to investigate the effect of icaritin (ICT) on TAR DNA-binding protein 43 (TDP-43)-induced neuroblastoma (SH-SY5Y) cell damage and to further explore its underlying mechanisms. METHODS: To investigate the possible mechanism, TDP-43 was used to induce SH-SY5Y cel...

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Detalles Bibliográficos
Autores principales: Zhou, Yongjian, Huang, Nanqu, Li, Yuanyuan, Ba, Zhisheng, Zhou, Yanjun, Luo, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362678/
https://www.ncbi.nlm.nih.gov/pubmed/34434670
http://dx.doi.org/10.7717/peerj.11978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362678/
https://www.ncbi.nlm.nih.gov/pubmed/34434670
http://dx.doi.org/10.7717/peerj.11978

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