MicroRNAs 21 and 199a-3p Regulate Axon Growth Potential through Modulation of Pten and mTor mRNAs

Increased mTOR activity has been shown to enhance regeneration of injured axons by increasing neuronal protein synthesis, while PTEN signaling can block mTOR activity to attenuate protein synthesis. MicroRNAs (miRs) have been implicated in regulation of PTEN and mTOR expression, and previous work in...

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Detalles Bibliográficos
Autores principales: Kar, Amar N., Lee, Seung-Joon, Sahoo, Pabitra K., Thames, Elizabeth, Yoo, Soonmoon, Houle, John D., Twiss, Jeffery L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362682/
https://www.ncbi.nlm.nih.gov/pubmed/34326064
http://dx.doi.org/10.1523/ENEURO.0155-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362682/
https://www.ncbi.nlm.nih.gov/pubmed/34326064
http://dx.doi.org/10.1523/ENEURO.0155-21.2021

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