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The challenge of structural heterogeneity in the native mass spectrometry studies of the SARS-CoV-2 spike protein interactions with its host cell-surface receptor

Native mass spectrometry (MS) enjoyed tremendous success in the past two decades in a wide range of studies aiming at understanding the molecular mechanisms of physiological processes underlying a variety of pathologies and accelerating the drug discovery process. However, the success record of nati...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Ivanov, Daniil G., Kaltashov, Igor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362873/
https://www.ncbi.nlm.nih.gov/pubmed/34389878
http://dx.doi.org/10.1007/s00216-021-03601-3