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A PGE(2)-MEF2A axis enables context-dependent control of inflammatory gene expression

Tight control of inflammatory gene expression by antagonistic environmental cues is key to ensure immune protection while preventing tissue damage. Prostaglandin E(2) (PGE(2)) modulates macrophage activation during homeostasis and disease, but the underlying mechanisms remain incompletely characteri...

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Detalles Bibliográficos
Autores principales: Cilenti, Francesco, Barbiera, Giulia, Caronni, Nicoletta, Iodice, Dario, Montaldo, Elisa, Barresi, Simona, Lusito, Eleonora, Cuzzola, Vincenzo, Vittoria, Francesco Maria, Mezzanzanica, Luca, Miotto, Paolo, Di Lucia, Pietro, Lazarevic, Dejan, Cirillo, Daniela Maria, Iannacone, Matteo, Genua, Marco, Ostuni, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362890/
https://www.ncbi.nlm.nih.gov/pubmed/34129840
http://dx.doi.org/10.1016/j.immuni.2021.05.016