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A PGE(2)-MEF2A axis enables context-dependent control of inflammatory gene expression
Tight control of inflammatory gene expression by antagonistic environmental cues is key to ensure immune protection while preventing tissue damage. Prostaglandin E(2) (PGE(2)) modulates macrophage activation during homeostasis and disease, but the underlying mechanisms remain incompletely characteri...
Autores principales: | Cilenti, Francesco, Barbiera, Giulia, Caronni, Nicoletta, Iodice, Dario, Montaldo, Elisa, Barresi, Simona, Lusito, Eleonora, Cuzzola, Vincenzo, Vittoria, Francesco Maria, Mezzanzanica, Luca, Miotto, Paolo, Di Lucia, Pietro, Lazarevic, Dejan, Cirillo, Daniela Maria, Iannacone, Matteo, Genua, Marco, Ostuni, Renato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362890/ https://www.ncbi.nlm.nih.gov/pubmed/34129840 http://dx.doi.org/10.1016/j.immuni.2021.05.016 |
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