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A novel artificial intelligence-based approach for identification of deoxynucleotide aptamers

The selection of a DNA aptamer through the Systematic Evolution of Ligands by EXponential enrichment (SELEX) method involves multiple binding steps, in which a target and a library of randomized DNA sequences are mixed for selection of a single, nucleotide-specific molecule. Usually, 10 to 20 steps...

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Detalles Bibliográficos
Autores principales: Heredia, Frances L., Roche-Lima, Abiel, Parés-Matos, Elsie I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362955/
https://www.ncbi.nlm.nih.gov/pubmed/34343165
http://dx.doi.org/10.1371/journal.pcbi.1009247