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Acute and endothelial-specific Robo4 deletion affect hematopoietic stem cell trafficking independent of VCAM1

Hematopoietic stem cell (HSC) trafficking is regulated by a number of complex mechanisms. Among them are the transmembrane protein Robo4 and the vascular cell adhesion molecule, VCAM1. Endothelial VCAM1 is a well-known regulator of hematopoietic cell trafficking, and our previous studies revealed th...

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Detalles Bibliográficos
Autores principales: Smith-Berdan, Stephanie, Bercasio, Alyssa, Kramer, Leah, Petkus, Bryan, Hinck, Lindsay, Forsberg, E. Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8362960/
https://www.ncbi.nlm.nih.gov/pubmed/34388149
http://dx.doi.org/10.1371/journal.pone.0255606