Nanoparticles of cisplatin augment drug accumulations and inhibit multidrug resistance transporters in human glioblastoma cells

BACKGROUND: Cisplatin (CSP) is a potent anticancer drug widely used in treating glioblastoma multiforme (GBM). However, CSP's clinical efficacy in GBM contrasted with low therapeutic ratio, toxicity, and multidrug resistance (MDR). Therefore, we have developed a system for the active targeting...

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Detalles Bibliográficos
Autores principales: Maliyakkal, Naseer, Appadath Beeran, Asmy, Udupa, Nayanabhirama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363105/
https://www.ncbi.nlm.nih.gov/pubmed/34408546
http://dx.doi.org/10.1016/j.jsps.2021.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363105/
https://www.ncbi.nlm.nih.gov/pubmed/34408546
http://dx.doi.org/10.1016/j.jsps.2021.07.001

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