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Nanoparticles of cisplatin augment drug accumulations and inhibit multidrug resistance transporters in human glioblastoma cells

BACKGROUND: Cisplatin (CSP) is a potent anticancer drug widely used in treating glioblastoma multiforme (GBM). However, CSP's clinical efficacy in GBM contrasted with low therapeutic ratio, toxicity, and multidrug resistance (MDR). Therefore, we have developed a system for the active targeting...

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Detalles Bibliográficos
Autores principales:	Maliyakkal, Naseer, Appadath Beeran, Asmy, Udupa, Nayanabhirama
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363105/ https://www.ncbi.nlm.nih.gov/pubmed/34408546 http://dx.doi.org/10.1016/j.jsps.2021.07.001

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