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Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells

BACKGROUND: Doxorubicin is one of the most effective chemotherapeutic drugs for breast cancer while its common drug resistance leads to poor patient prognosis and survival. Growing evidence indicate dynamically reorganized chromatin allows rapid access of the gene regulatory machinery to open genomi...

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Detalles Bibliográficos
Autores principales: Wang, Xuelong, Yan, Jizhou, Shen, Baiyong, Wei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363264/
https://www.ncbi.nlm.nih.gov/pubmed/34395436
http://dx.doi.org/10.3389/fcell.2021.708066