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The Promise of Personalized TCR-Based Cellular Immunotherapy for Cancer Patients

Mutation-derived neoantigens are now established as attractive targets for cancer immunotherapy. The field of adoptive T cell transfer (ACT) therapy was significantly reshaped by tumor neoantigens and is now moving towards the genetic engineering of T cells with neoantigen-specific T cell receptors...

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Detalles Bibliográficos
Autores principales: Arnaud, Marion, Bobisse, Sara, Chiffelle, Johanna, Harari, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363295/
https://www.ncbi.nlm.nih.gov/pubmed/34394096
http://dx.doi.org/10.3389/fimmu.2021.701636