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Hypothesis and Theory: Characterizing Abnormalities of Energy Metabolism Using a Cellular Platform as a Personalized Medicine Approach for Alzheimer’s Disease

Sporadic or late-onset Alzheimer’s disease (LOAD) is characterized by slowly progressive deterioration and death of CNS neurons. There are currently no substantially disease-modifying therapies. LOAD pathology is closely related to changes with age and include, among others, accumulation of toxic mo...

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Detalles Bibliográficos
Autores principales: Ryu, Woo-In, Cohen, Bruce M., Sonntag, Kai-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363296/
https://www.ncbi.nlm.nih.gov/pubmed/34395428
http://dx.doi.org/10.3389/fcell.2021.697578