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FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells

Previous studies have established the pathogenic role of advanced glycation end products (AGEs) accumulation in intervertebral disc degeneration (IDD). Emerging evidence indicates that ER-phagy serves as a crucial cellular adaptive mechanism during stress conditions. This study is aimed at investiga...

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Detalles Bibliográficos
Autores principales: Luo, Rongjin, Li, Shuai, Li, Gaocai, Lu, Saideng, Zhang, Weifeng, Liu, Hui, Lei, Jie, Ma, Liang, Ke, Wencan, Liao, Zhiwei, Wang, Bingjin, Song, Yu, Wang, Kun, Zhang, Yukun, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363461/
https://www.ncbi.nlm.nih.gov/pubmed/34394825
http://dx.doi.org/10.1155/2021/3843145