Optimization of antigen-specific CD8(+) T cell activation conditions for infectious diseases including COVID-19

Here, we describe the use of the artificial antigen-presenting cell (aAPC) system for the verification of T-cell epitopes. We purify and activate CD8(+) T cells from blood samples from HLA-A2 that are negative for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). CD8(+) T cells are combi...

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Detalles Bibliográficos
Autores principales: Xiao, Chanchan, Qiu, Congling, Deng, Jieping, Ye, Jiezhou, Gao, Lijuan, Su, Jun, Luo, Oscar Junhong, Wang, Pengcheng, Chen, Guobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363473/
https://www.ncbi.nlm.nih.gov/pubmed/34414379
http://dx.doi.org/10.1016/j.xpro.2021.100789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363473/
https://www.ncbi.nlm.nih.gov/pubmed/34414379
http://dx.doi.org/10.1016/j.xpro.2021.100789

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