VEGFR-2 kinase domain inhibition as a scaffold for anti-angiogenesis: Validation of the anti-angiogenic effects of carotenoids from Spondias mombin in DMBA model of breast carcinoma in Wistar rats

Vascular endothelial growth factor (VEGF) and its receptor-2 (VEGFR-2) mediated tumorigenesis, metastasis, and angiogenesis are the cause of the increased levels of mortality associated with breast cancer and other forms of cancer. Inhibition of VEGF and VEGFR-2 provides a great therapeutic option i...

Descripción completa

Detalles Bibliográficos
Autores principales: Metibemu, Damilohun Samuel, Akinloye, Oluseyi Adeboye, Akamo, Adio Jamiu, Okoye, Jude Ogechukwu, Ojo, David Ajiboye, Morifi, Eric, Omotuyi, Idowu Olaposi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363596/
https://www.ncbi.nlm.nih.gov/pubmed/34408968
http://dx.doi.org/10.1016/j.toxrep.2021.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363596/
https://www.ncbi.nlm.nih.gov/pubmed/34408968
http://dx.doi.org/10.1016/j.toxrep.2021.02.011

Ejemplares similares