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VEGFR-2 kinase domain inhibition as a scaffold for anti-angiogenesis: Validation of the anti-angiogenic effects of carotenoids from Spondias mombin in DMBA model of breast carcinoma in Wistar rats

Vascular endothelial growth factor (VEGF) and its receptor-2 (VEGFR-2) mediated tumorigenesis, metastasis, and angiogenesis are the cause of the increased levels of mortality associated with breast cancer and other forms of cancer. Inhibition of VEGF and VEGFR-2 provides a great therapeutic option i...

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Detalles Bibliográficos
Autores principales:	Metibemu, Damilohun Samuel, Akinloye, Oluseyi Adeboye, Akamo, Adio Jamiu, Okoye, Jude Ogechukwu, Ojo, David Ajiboye, Morifi, Eric, Omotuyi, Idowu Olaposi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363596/ https://www.ncbi.nlm.nih.gov/pubmed/34408968 http://dx.doi.org/10.1016/j.toxrep.2021.02.011

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